Neurogenesis in the Adult Mammalian Brain – Implications for Self Repair and Treatment of Acute Brain Trauma
AbstractThe adult mammalian brain, previously thought to be incapable of repair after acute injury, is now known to contain discreet populations of neural cell progenitors. These stem cells have been shown to proliferate and establish neural connections in response to acute brain injury. This may represent a capacity for self repair that can be used to restore loss of cognitive abilities and movement associated with ischaemia, stroke and other acute trauma. This essay examines both the potential and limitations of stimulating the proliferation of endogenous neural stem cells.